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Cat Number: API333963409

Lubiprostone

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CAS Number

333963-40-9

Synonyms

Amitiza
RU-0211
Lubiprostone hemiketal

Description

Lubiprostone is a medication used in the management of idiopathic chronic constipation. A prostaglandin E1 derivative, lubiprostone is a bicyclic fatty acid that activates ClC-2 chloride channels located on the apical side of the gastrointestinal epithelial cells. Activation of these channels promotes the secretion of a chloride-rich fluid that soften the stool, increase gastrointestinal motility, and induce spontaneous bowel movements

Molecular Weight

390.5

Molecular Formula

C20H32F2O5

SMILES

CCCCC(C1(CCC2C(O1)CC(=O)C2CCCCCCC(=O)O)O)(F)F

Appearance

Off-white Solid

Boiling Point

532.3±50.0 ℃ at 760 Torr

Density, g/cm3

1.175±0.06

Note

USDMF 30802

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