Cat Number: API1223403584

LOXO-101

CAS Number

1223403-58-4

Synonyms

CS-2322;LOXO101;LOXO 101;LOXO-101,LAROTRECTINIB,ARRY-470 (LAROTRECTINIB SULFATE CAS:1223405-08-0);(R)-N-(5-((S)-2-(2,5-difluorophenyl)pyrrolidin-1-yl)pyrazolo[1,5-a]pyrimidin-3-yl)-3-hydroxypyrrolidine-1-carboxamide;LOXO-101 Larotrectinib;LOXO-101 (ARRY-470,Larotrectinib);LOXO-101,LAROTRECTINIB,ARRY-470

Description

LOXO-101 is a drug used to treat adults and children with certain types of solid tumors that have spread or cannot be removed by surgery and have the NTRK gene fusion.

Molecular Weight

428.44

Molecular Formula

C21H22F2N6O2

Appearance

solid

Color

Yellow

Storage

pKa

8.41±0.40(Predicted)

Density, g/cm3