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Cat Number: API668270120

Linagliptin

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CAS Number

668270-12-0

Synonyms

Tradjenta;Ondero;BI-1356

Description

Linagliptin is a DPP-4 inhibitor developed by Boehringer Ingelheim for the treatment of type II diabetes. Linagliptin differs from other DPP-4 inhibitors in that it has a non-linear pharmacokinetic profile, is not primarily eliminated by the renal system, and obeys concentration dependant protein binding.

Molecular Weight

472.5

Molecular Formula

C25H28N8O2

SMILES

CC#CCN1C2=C(N=C1N3CCCC(C3)N)N(C(=O)N(C2=O)CC4=NC5=CC=CC=C5C(=N4)C)C

EINECS

620-351-9

Appearance

White to yellow solid

Melting Point

202 °C