Cat Number: API1180718

Limonin

APIs
CAS Number
1180-71-8
Description
Limonin is a triterpenoid enriched in citrus fruits, which has antivirus and antitumor ability.IC50 Value: Target: HIV; anticancerLimonin is a triterpenoid aglycone that is a bitter principle of citrus fruits. Limonin is chemically induced carcinogenesis inhibitor and HIV-1 replication inhibitor. Limonin has anti-proliferative, proapoptotic activity on several cancer cell lines and inhibits azoxymethane-induced colon cancer in rats. Limonin also inhibits HIV-1 replication in culturedf monocytes, macrophages, and mononuclear cells, perhaps by inhibition of HIV-1 protease activity.
MolecularWeight
470.512
MolecularFormula
C26H30O8
SMILEs
C[C@@]12CC[C@H]3[C@]([C@@]14[C@H](O4)C(=O)O[C@H]2C5=COC=C5)(C(=O)C[C@@H]6[C@@]37COC(=O)C[C@@H]7OC6(C)C)C
Solubility
Soluble in ethanol
Storage
Store at -20℃
MeltingPoint
298ºC
BoilingPoint
668.4±55.0 ℃ at 760 mmHg
Density
1.39 g/cm3
RefractiveIndex
1.602
OpticalActivity
α20D -128, c = 1.21 in acetone
FlashPoint
358.0±31.5 ℃
VapourPressure
0.0±2.0 mmHg at 25℃
Specification
1-98% HPLC
PreparationUse
Analgesic and anti-inflammatory effect
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