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Cat Number: API1025967785

Lifitegrast

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CAS Number

1025967-78-5

Synonyms

Xiidra SAR-1118 SAR 1118

Description

Lifitegrast is a FDA approved drug for the treatment of keratoconjunctivitis sicca (dry eye syndrome). It is a tetrahydroisoquinoline derivative and lymphocyte function-associated antigen-1 ( LFA-1) antagonist that was discovered through the rational design process.

Molecular Weight

615.5

Molecular Formula

C29H24Cl2N2O7S

SMILES

CS(=O)(=O)C1=CC=CC(=C1)CC(C(=O)O)NC(=O)C2=C(C=C3CN(CCC3=C2Cl)C(=O)C4=CC5=C(C=C4)C=CO5)Cl

EINECS

813-044-8

Appearance

Solid Powder

Boiling Point

811.9±65.0 ℃ at 760 mmHg