Cat Number: API59927

Levodopa

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CAS Number

59-92-7

Description

Levodopa is an immediate precursor of dopamine and product of tyrosine hydroxylase

MolecularWeight

197.19

MolecularFormula

C9H11NO4

Appearance

Crystalline powder

Solubility

Soluble in water (3 mg/ml), DMSO

Storage

Store at -20℃

MeltingPoint

276-278℃ (lit.)

BoilingPoint

~448.4℃ at 760 mmHg

Density

~1.5 g/cm³

RefractiveIndex

~1.66

OpticalActivity

α25D -11.5±1, c = 1 in hydrochloric acid

IC50

Fyn: IC50 = 2.15 µM (human); 15-LO: IC50 = 2.26 µM (human); EGFR: IC50 = 2.88 µM (human); Lck: IC50 = 3.73 µM (human); Tyrosinase: IC50 = 8.4 mM (human)

pKValue

pKa: pK1: 2.3, pK2: 8.7, pK3: 9.7, pk4: 13.4, (25 C). pKb: 8.85

Specification

Antiparkinson drugs

PreparationUse

Levodopa tablets (0.25 g)

Standard

Chinese Pharmacopoeia 2015 Edition Part 2

HOURS

Daily: 9.30 AM–6.00 PM
Sunday : 9.30 AM–1.00 PM
Holidays: Closed

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