Cat Number: API134678174

Lamivudine

Inquiry

CAS Number

134678-17-4

Description

Lamivudine is a potent reverse transcriptase inhibitor.

Molecular Weight

229.26

Molecular Formula

C8H11N3O3S

Solubility

Soluble in water (46 mg/ml at 25℃), DMSO (46 mg/ml at 25℃), methanol, and ethanol

Storage

Store at 4℃

SMILES

C1[C@H](O[C@H](S1)CO)N2C=CC(=NC2=O)N

Appearance

Powder

pKa

13.83

Boiling Point

~475.4℃ at 760 mmHg

Density, g/cm3

1.7

Optical Activity

α20D -142±5, c = 1 in methanol

IC50

ADMET: IC50 = 2 nM; Human immunodeficiency virus 1: IC50 = 21.8 nM; Hepatitis B virus: IC50 = 50 nM; MT4: IC50 = 100 nM (human); Anas sp.: IC50 = 100 nM

Melting Point

175-177℃

Flash Point

241.3±31.5 ℃

Vapour Pressure

0.0±2.7 mmHg at 25℃

Standard

Facility GMP

Specification

Used along with other medications to treat human immunodeficiency virus (HIV) infection in adults and children 3 months of age and older.

Preparation Use

Tablets

Qualification

USMF/CEP/KDMF

HOURS

Daily: 9.30 AM–6.00 PM
Sunday : 9.30 AM–1.00 PM
Holidays: Closed

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