Description
(−)Epicatechin is a natural product from green tea. (−)Epicatechin is an inhibitor of Cox-1.
MolecularFormula
C15H14O6
SMILEs
C1[C@H]([C@H](OC2=CC(=CC(=C21)O)O)C3=CC(=C(C=C3)O)O)O
Solubility
Soluble in acetone:water (1:1, 10 mg/ml), DMSO (100 mM), methanol, DMF (~12.5 mg/ml), and water (partly).
MeltingPoint
240 ℃ (dec.)(lit.)
BoilingPoint
630.4±55.0 ℃ at 760 mmHg
IC50
TNAP: IC50 = 407 nM (human); Intestinal alkaline phosphatase: IC50 = 1.36 µM (mouse); M18 aspartyl aminopeptidase: IC50 = 1.38 µM (Plasmodium falciparum 3D7); Cyclooxygenase-1: IC50 = 2.00 µM (sheep); Cox-1: IC50 = 3.2 µM
pKValue
pKa: 9.54 (Predicted), pKb: -3.3 (Predicted)
VapourPressure
0.0±1.9 mmHg at 25℃
Specification
90%, 95%, 98% HPLC
PreparationUse
Antioxidant activity