Cat Number: 91306ES

KFG-2/FGF-10-1

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Genus

Human

Source

E.coli

Synonyms

FGF10, FGF-10, fibroblast growth factor 10, Keratinocyte growth factor 2, KGF2, KGF-2

Description

Fibroblast growth factor 10 (FGF-10) is a heparin-binding growth factor that belongs to the FGF family. Proteins of this family play a central role in prenatal development, postnatal growth, and regeneration of various tissues by promoting cell proliferation and differentiation.FGF-10 is most closely related to KGF/FGF-7, and is expressed during development, preferentially in the adult lung. It signals through FGFR 2b.

Molecular Weight

Approximately 19.1 kDa.

Appearance

Sterile Filtered White lyophilized (freeze-dried) powder.

Purity

>97% by SDS-PAGE analyses.

Biological Activity

The ED50 as determined by thymidine uptake assay using FGF-receptors transfected BaF3 cells is less than 0.5 ng/mL, corresponding to a specific activity of > 2.0 × 106 IU/mg. Fully biologically active when compared to standard.

Endotoxin

<1.0 EU/μg

Formulation

Lyophilized from a 0.2 μm filtered concentrated solution in 2 × PBS, pH 7.4.

Reconstitution

Brief centrifugation prior to opening is recommended to bring the contents to the bottom. Reconstitute to a concentration of 0.1-1.0 mg/mL in sterile distilled water or an aqueous buffer containing 0.1% BSA. The stock solution should be divided into aliquots and stored at ≤ -20°C.

Note

2, 10, 50, 100, 500μg, 1mg

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Sunday : 9.30 AM–1.00 PM
Holidays: Closed

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