Description
Ketorolac (tromethamine salt) is a non selective inhibitior of Cox-1 and Cox-2
Molecular Formula
C15H12NO3•C4H12NO3
Solubility
Soluble in ethanol (~7 mg/ml), DMF (~50 mg/ml), DMSO (~7 mg/ml), water (15 mg/ml), and methanol.
Storage
Desiccate at room temperature
IC50
COX-1: IC50 = 1.23 µM; COX-2: IC50 = 3.50 µM; Recombinant COX-1: IC50 = 31.5 µM (human); Recombinant COX-2: IC50 = 60.5 µM (human)
Standard
USP
Facility GMP
Product GMP
Preparation Use
nonsteroidal anti-inflammatory dug (NSAID)