Description
Ketoprofen is an inhibitor of Cox-1 and Cox-2
MolecularFormula
C16H14O3
Appearance
Crystalline powder
Solubility
Soluble in ethanol (51 mg/ml at 25℃), DMSO (51 mg/ml at 25℃), water.
BoilingPoint
403.3-459.3℃ at 760 mmHg
IC50
Cox-1: IC50 = 2 nM (human); Cox-2: IC50 = 26 nM (human); rat: IC50 = 200 nM; Solute carrier family 22 member 6: IC50 = 500 nM (rat); OAT1: IC50 = 1.3 µM (human)
PreparationUse
Non-steroid anti-inflammatory