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Cat Number: API155270998

Istradefylline

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CAS Number

155270-99-8

Synonyms

KW-6002
nouriast
Nourianz

Description

Istradefylline is an adenosine receptor antagonist that is used as adjunctive therapy to levodopa/carbidopa in patients with Parkinson disease experiencing difficulty with “off” episodes when motor symptoms breakthrough on treatment. Istradefylline has been associated with a low rate of serum enzyme elevations during therapy, but has not been linked to cases of clinically apparent liver injury with jaundice.

Molecular Weight

384.4

Molecular Formula

C20H24N4O4

SMILES

CCN1C2=C(C(=O)N(C1=O)CC)N(C(=N2)C=CC3=CC(=C(C=C3)OC)OC)C

EINECS

803-302-8

Appearance

Pale Green Solid

Melting Point

189-193