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Cat Number: PIPE-0623

Isoliquiritigenin

CAS Number

961-29-5

Synonyms

Trihydroxychalcone
2',4,4'-Trihydroxychalcone
(E)-1-(2,4-dihydroxyphenyl)-3-(4-hydroxyphenyl)prop-2-en-1-one
4,2',4'-Trihydroxychalcone

Description

Isoliquiritigenin is a member of the class of chalcones that is trans-chalcone hydroxylated at C-2', -4 and -4'. It has a role as an EC 1.14.18.1 (tyrosinase) inhibitor, a biological pigment, a NMDA receptor antagonist, a GABA modulator, a metabolite, an antineoplastic agent and a geroprotector. It is functionally related to a trans-chalcone. It is a conjugate acid of an isoliquiritigenin(1-).

Molecular Weight

256.25

Molecular Formula

C15H12O4

EINECS

237-316-5

SMILES

C1=CC(=CC=C1C=CC(=O)C2=C(C=C(C=C2)O)O)O

Appearance

Yellow powder

Storage

Room temperature