Synonyms
Trihydroxychalcone
2',4,4'-Trihydroxychalcone
(E)-1-(2,4-dihydroxyphenyl)-3-(4-hydroxyphenyl)prop-2-en-1-one
4,2',4'-Trihydroxychalcone
Description
Isoliquiritigenin is a member of the class of chalcones that is trans-chalcone hydroxylated at C-2', -4 and -4'. It has a role as an EC 1.14.18.1 (tyrosinase) inhibitor, a biological pigment, a NMDA receptor antagonist, a GABA modulator, a metabolite, an antineoplastic agent and a geroprotector. It is functionally related to a trans-chalcone. It is a conjugate acid of an isoliquiritigenin(1-).
Molecular Formula
C15H12O4
SMILES
C1=CC(=CC=C1C=CC(=O)C2=C(C=C(C=C2)O)O)O
Boiling Point
504.0±42.0℃ (Predicted)
Density, g/cm3
1.384±0.06 (Predicted)
Melting Point
200 - 204 ℃
Applications
antidiabetic; antitumour; antioxidant; anti-inflammatory; antimutagenic; antifungal;