Cat Number: API220127571-2

Imatinib Mesylate(α form)

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CAS Number

220127-57-1

Synonyms

Gleevec
Glivec
Imatinib mesilate

Description

A tyrosine kinase inhibitor and ANTINEOPLASTIC AGENT that inhibits the BCR-ABL kinase created by chromosome rearrangements in CHRONIC MYELOID LEUKEMIA and ACUTE LYMPHOBLASTIC LEUKEMIA, as well as PDG-derived tyrosine kinases that are overexpressed in gastrointestinal stromal tumors.

Molecular Weight

589.7

Molecular Formula

C30H35N7O4S

SMILES

CC1=C(C=C(C=C1)NC(=O)C2=CC=C(C=C2)CN3CCN(CC3)C)NC4=NC=CC(=N4)C5=CN=CC=C5.CS(=O)(=O)O

EINECS

606-892-3

Appearance

White to off white to brownish or yellowish tinged crystalline powder

Melting Point

214-224℃