Cat Number: INT68594069

Idarubicin HCL Intermediates 2

CAS Number

68594-06-9

Synonyms

N-(Trifluoroacetyl)-1-desmethyl Daunorubicin
N-[(2S,3S,4S,6R)-6-[[(1S,3S)-3-acetyl-3,5,10,12-tetrahydroxy-6,11-dioxo-2,4-dihydro-1H-tetracen-1-yl]oxy]-3-hydroxy-2-methyloxan-4-yl]-2,2,2-trifluoroacetamide
DTXSID40570353
(1S,3S)-3-Acetyl-3,5,10,12-tetrahydroxy-6,11-dioxo-1,2,3,4,6,11-hexahydrotetracen-1-yl 2,3,6-trideoxy-3-(2,2,2-trifluoroacetamido)-alpha-L-lyxo-hexopyranoside

Description

N-(Trifluoroacetyl)-1-desmethyl Daunorubicin is a derivative of Daunorubicin, which is an anthracycline antibiotic used in the treatment of acute myeloid and lymphocytic leukemia, with adverse reactions such as cardiotoxicity and bone marrow suppression.

Molecular Weight

609.5

Molecular Formula

C28H26F3NO11

SMILES

CC1C(C(CC(O1)OC2CC(CC3=C2C(=C4C(=C3O)C(=O)C5=C(C4=O)C(=CC=C5)O)O)(C(=O)C)O)NC(=O)C(F)(F)F)O

Appearance

Red Solid

Boiling Point

798.5±60.0℃ at 760 mmHg

Density, g/cm3

1.7±0.1