Cat Number: API15687271

Ibuprofen

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CAS Number

15687-27-1

Description

Ibuprofen is an anti-inflammatory inhibitor targeting COX-1 and COX-2 with IC50 of 13 μM and 370 μM, respectively.

Molecular Weight

206.281

Molecular Formula

C13H18O2

Solubility

Soluble in ethanol (25 mg/ml), chloroform (1:1), ether (1:2), acetone (1:1.5), aqueous solutions of alkali hydroxides and carbonates, dichloromethane, methanol (50 mg/ml), and ethyl acetate. Insoluble in water.

Storage

Store at -20℃

SMILES

CC(C)CC1=CC=C(C=C1)C(C)C(=O)O

pKa

pKa: 5.2

Boiling Point

319.6±11.0 ℃ at 760 mmHg

Density, g/cm3

1.0±0.1

IC50

COX-1: IC50 = 2.6 µM (human); COX-2: IC50 = 1.5 µM (human); COX-1: IC50 = 2.9 µM (Ovis aries); COX-2: IC50 = 1.1 µM (Ovis aries)

Melting Point

77-78 ℃(lit.)

Refractive Index

1.519

Flash Point

216.7±14.4 ℃

Vapour Pressure

0.0±0.7 mmHg at 25℃

Standard

Facility GMP

Specification

A non-steroidal anti-inflammatory analgesic.

Preparation Use

Tablets

Qualification

DMF

HOURS

Daily: 9.30 AM–6.00 PM
Sunday : 9.30 AM–1.00 PM
Holidays: Closed

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