Cat Number: INT936563961

Ibrutinib Intermediate 2

APIs
CAS Number
936563-96-1
Synonyms
Ibrutinib
PCI-32765
IMBRUVICA
PCI 32765
Description
Ibrutinib is a small molecule that acts as an irreversible potent inhibitor of Burton's tyrosine kinase. It is designated as a targeted covalent drug and presented as a promising activity in B-cell malignancies in clinical trials.
Molecular Weight
440.5
Molecular Formula
C25H24N6O2
SMILES
C=CC(=O)N1CCCC(C1)N2C3=NC=NC(=C3C(=N2)C4=CC=C(C=C4)OC5=CC=CC=C5)N
EINECS
805-642-2
Appearance
White to off-white solid
pKa
3.74
Melting Point
149-158ºC
Application
Ibrutinib Intermediates
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