Synonyms
Ibrutinib
PCI-32765
IMBRUVICA
PCI 32765
Description
Ibrutinib is a small molecule that acts as an irreversible potent inhibitor of Burton's tyrosine kinase. It is designated as a targeted covalent drug and presented as a promising activity in B-cell malignancies in clinical trials.
Molecular Formula
C25H24N6O2
SMILES
C=CC(=O)N1CCCC(C1)N2C3=NC=NC(=C3C(=N2)C4=CC=C(C=C4)OC5=CC=CC=C5)N
Appearance
White to off-white solid
Application
Ibrutinib Intermediates