Heavy Metal Test

Heavy metal impurities refer to metals or metal elements with higher density, atomic weight, or atomic number.

In the pharmaceutical industry, these impurities are often found in products, originating from sources such as metal catalysts and environmental pollutants found in raw materials and excipients. Certain heavy metals such as Pb, Hg, Cr, and As have high toxicity and carcinogenic properties.

When these metals enter the human body, they disrupt the normal function of enzymes responsible for controlling the speed of metabolic reactions and can cause harm to organs and the nervous system. Even essential heavy metals for life, such as Fe, Zn, and Co, can cause poisoning or adverse reactions if consumed in excess or in biologically harmful forms.

Services Process

1. Sample Collection and Method Selection

Upon receiving the samples, our team of experts carefully handles and prepares them for analysis.

We choose the appropriate analytical method based on the properties of the samples. For the detection of heavy metal impurities, we employ various methods, including Colorimetric, Inductively Coupled Plasma Mass Spectrometry (ICP-MS), and Inductively Coupled Plasma Atomic Emission Spectroscopy (ICP-AES).

2. Analysis

We rigorously handle the samples to test the presence of heavy metal elements. Our testing methods adhere to strict regulatory guidelines, These methods ensure that our testing is conducted in compliance with regulatory standards.

Here are some typical methods used for Heavy metal impurities testing:

• Colorimetric Method - This method is relatively straightforward and doesn't require complex instrumentation so it tends to be less expensive compared to mass spectrometry techniques. The results may not be as precise or accurate as those from more advanced methods.
• ICP-MS - Capable of performing isotope analysis for precise identification. It offers exceptional sensitivity and can detect elements at very low concentrations.
• ICP-AES - In the field of isotope analysis it is not as capable as ICP-MS in performing isotope analysis.

3. Data Analysis and Report Generation

Our experienced analytical chemists analyze the data obtained from the analysis and generate comprehensive reports.

These reports include information about the detected heavy metal impurities, their concentrations, chemical characteristics, and any other relevant findings. These reports serve as references for product formulation and regulatory compliance.

4. Follow-up Support

If clients have any concerns or questions during the consultation, we provide expert guidance and solutions to address them.

Protheragen-ING offers professional services for heavy metal impurity detection, ensuring the quality and safety of pharmaceutical products. If you need more information, please contact us, and we will respond within 2-4 working days.