Cat Number: PIPB-0754

H-HYP-OME.HCl

CAS Number

40216-83-9

Synonyms

(2S,4R)-methyl 4-hydroxypyrrolidine-2-carboxylate hydrochloride
trans-4-Hydroxy-L-proline methyl ester hydrochloride
Methyl (2S,4R)-4-hydroxypyrrolidine-2-carboxylate Hydrochloride

Description

H-Hyp-OMe hydrochloride is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). It is also an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs.

Molecular Weight

181.62

Molecular Formula

C6H12ClNO3

EINECS

609-795-4

SMILES

COC(=O)C1CC(CN1)O.Cl

Appearance

White or off-white crystalline powder

Boiling Point

247.2℃ at 760 mmHg