Cat Number: INT1033769286

GNF 5837

APIs
CAS Number
1033769-28-6
Synonyms
Trk Inhibitor III, GNF-5837 - CAS 1033769-28-6 - Calbiochem;CS-997;GNF5837; GNF 5837;Trk Inhibitor III, GNF-5837;GNF 5837;(Z)-1-(3-(3-((1H-PYRROL-2-YL)METHYLENE)-2-OXOINDOLIN-6-YLAMINO)-4-METHYLPHENYL)-3-(2-FLUORO-5-(TRIFLUOROMETHYL)PHENYL)UREA;N-[3-[[2,3-Dihydro-2-oxo-3-(1H-pyrrol-2-ylmethylene)-1H-indol-6-yl]amino]-4-methylphenyl]-N'-[2-fluoro-5-(trifluoromethyl)phenyl]-urea
Description
GNF 5837 is a potent pan-Trk inhibitor which has selectivity for tropomyosin-receptor-kinase (Trk).
Molecular Weight
535.49
Molecular Formula
C28H21F4N5O2
Appearance
powder
Color
yellow to orange
Storage
2-8 ℃
pKa
12.16±0.20(Predicted)
Boiling Point
616.0±55.0 ℃(Predicted)
Density, g/cm3
1.497±0.06(Predicted)
Melting Point
>228 ℃ (dec.)
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