Cat Number: 92520ES

GMF-β

Inquiry

Genus

Human

Source

E.coli

Synonyms

GMFB

Description

GMF-beta belongs to the actin-binding ADF/cofilin protein family. It contains an ADF-H domain, but the research of crystallography and NMR reveals that there are structures different between human and mouse ADF-H domain. It was initially identified as a growth gamma differentiation factor that acts on neurons and glia. It has also been shown to function intracellularly as a modulator of MAP kinase signal transduction.

Molecular Weight

Approximately 16.6 kDa.

AA sequence

SESLVVCDVA EDLVEKLRKF RFRKETNNAA IIMKIDKDKR LVVLDEELEG ISPDELKDEL PERQPRFIVY SYKYQHDDGR VSYPLCFIFS SPVGCKPEQQ MMYAGSKNKL VQTAELTKVF EIRNTEDLTE EWLREKLGFF H

Appearance

Sterile Filtered White lyophilized (freeze-dried) powder.

Purity

> 98% by SDS-PAGE and HPLC analyses.

Endotoxin

< 1.0 EU per 1μg of the protein by the LAL method.

Formulation

Lyophilized from a 0.2 μm filtered concentrated solution in 20 mM PB, pH 7.4, 130 mM NaCl.

Reconstitution

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0 mg/mL. Stock solutions should be apportioned into working aliquots and stored at ≤ -20℃. Further dilutions should be made in appropriate buffered solutions.

Note

2, 10, 50, 100μg, 1mg

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Sunday : 9.30 AM–1.00 PM
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