Cat Number: API29094619

Glipizide

APIs
CAS Number
29094-61-9
Synonyms
Glucotrol
Glydiazinamide
Dipazide
Description
Glipizide is an N-sulfonylurea that is glyburide in which the (5-chloro-2-methoxybenzoyl group is replaced by a (5-methylpyrazin-2-yl)carbonyl group. An oral hypoglycemic agent, it is used in the treatment of type 2 diabetes mellitus. It has a role as a hypoglycemic agent, an EC 2.7.1.33 (pantothenate kinase) inhibitor and an insulin secretagogue. It is a N-sulfonylurea, a member of pyrazines, an aromatic amide and a monocarboxylic acid amide.
Molecular Weight
445.5
Molecular Formula
C21H27N5O4S
SMILES
CC1=CN=C(C=N1)C(=O)NCCC2=CC=C(C=C2)S(=O)(=O)NC(=O)NC3CCCCC3
EINECS
249-427-6
Appearance
White to Off-white Solid
pKa
5.9
Density, g/cm3
1.34±0.1
Melting Point
208 - 209 ℃
Qualification
GMP
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