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Cat Number: API29094619

Glipizide

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CAS Number

29094-61-9

Synonyms

Glucotrol
Glydiazinamide
Dipazide

Description

Glipizide is an N-sulfonylurea that is glyburide in which the (5-chloro-2-methoxybenzoyl group is replaced by a (5-methylpyrazin-2-yl)carbonyl group. An oral hypoglycemic agent, it is used in the treatment of type 2 diabetes mellitus. It has a role as a hypoglycemic agent, an EC 2.7.1.33 (pantothenate kinase) inhibitor and an insulin secretagogue. It is a N-sulfonylurea, a member of pyrazines, an aromatic amide and a monocarboxylic acid amide.

Molecular Weight

445.5

Molecular Formula

C21H27N5O4S

SMILES

CC1=CN=C(C=N1)C(=O)NCCC2=CC=C(C=C2)S(=O)(=O)NC(=O)NC3CCCCC3

EINECS

249-427-6

Appearance

White to Off-white Solid

pKa

5.9