Cat Number: INT1095173275

Glasdegib

CAS Number

1095173-27-5

Synonyms

EOS-60832;PF 04449913;1-((2R,4R)-2-(1H-benzo[d]iMidazol-2-yl)-1-Methylpiperidin-4-yl)-3-(4-cyanophenyl)urea;N-[(2R,4R)-2-(1H-Benzimidazol-2-yl)-1-methyl-4-piperidinyl]-N'-(4-cyanophenyl)urea;Glasdegib (PF-04449913);N-[(2R,4R)-2-(1H-Benzimidazol-2-yl)-1-methyl-4-piperidinyl]-N'-(4-cyanophenyl)urea PF 04449913;CS-1041

Description

Glasdegib acts as a potent, orally biovailablesmoothened (Smo) inhibitor used in the treatment of cancer.

Molecular Weight

374.44

Molecular Formula

C21H22N6O

InChI

SFNSLLSYNZWZQG-VQIMIIECSA-N

InChIKey

SFNSLLSYNZWZQG-VQIMIIECSA-N

SMILES

N([C@@H]1CCN(C)[C@@H](C2NC3=CC=CC=C3N=2)C1)C(NC1=CC=C(C#N)C=C1)=O

Appearance

Solid

Color

Off-White

Storage

-20 ℃ Freezer

pKa

11.93±0.10(Predicted)

Boiling Point

633.4±55.0 ℃(Predicted)

Density, g/cm3

1.33±0.1(Predicted)

Melting Point

>214 ℃ (dec.)

HOURS

Daily: 9.30 AM–6.00 PM
Sunday : 9.30 AM–1.00 PM
Holidays: Closed

INFORMATION

Tel:
E-mail:
Address:
WhatsAPP

Member of