Cat Number: API184475352

Gefitinib

CAS Number

184475-35-2

Description

Gefitinib is an EGFR-tyrosine kinase inhibitor.

MolecularWeight

446.9

MolecularFormula

C22H24ClFN4O3

Solubility

Soluble in DMSO (89 mg/ml at 25℃), methanol (20 mg/ml), ethanol (4 mg/ml at 25℃), DMF (20 mg/ml), and water

Storage

Store at -20℃

MeltingPoint

193-194℃

BoilingPoint

~586.8℃ at 760 mmHg

Density

~1.3 g/cm³

RefractiveIndex

1.62

IC50

EGFR: IC50 = 1 nM; HCC827 cell: IC50 = 1.5 nM (human); BA/F3 cells: IC50 = 10.8 nM (mouse); NCI-H292: IC50 = 20 nM; FaDu: IC50 = 50 nM (human)

pKValue

pKb: 7

PreparationUse

Anti-cancer

HOURS

Daily: 9.30 AM–6.00 PM
Sunday : 9.30 AM–1.00 PM
Holidays: Closed

INFORMATION

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