Cat Number: PIPB-0508

Fmoc-Glu(OtBu)-OH

CAS Number

71989-18-9

Synonyms

N-ALPHA-FMOC-L-GLUTAMIC ACID GAMMA-T-BUTYL ESTER;N-ALPHA-FMOC-L-GLUTAMIC ACID GAMMA-TERT-BUTYL ESTER;N-9-FLUORENYLMETHYLOXYCARBONYL-L-GLUTAMIC ACID GAMMA-T-BUTYL ESTER;N-9-FLUORENYLMETHYLOXYCARBONYL-L-GLUTAMIC ACID GAMMA-TERT-BUTYL ESTER;N-ALPHA-(9-FLUORENYLMETHYLOXYCARBONYL)-L-GLUTAMIC-ACID-GAMMA-T-BUTYL ESTER;N-ALPHA-(9-FLUORENYLMETHOXYCARBONYL)-GAMMA-T-BUTYL-L-GLUTAMIC ACID;N-FMOC-L-GLUTAMIC ACID GAMMA-T-BUTYL ESTER;N-FMOC-O-T-BUTYL-L-GLU

Description

Fmoc-Glu(OtBu)-OH can be employed as a ligand in the synthesis of cis-substituted cyclopropane carboxylic acids via C-H activation of cyclopropane carboxamides using Pd catalyst. It can be also used as a building block in the preparation of stapled α-helical peptides, and peptide C-terminal thioesters.

Molecular Weight

425.47

Molecular Formula

C24H27NO6

EINECS

276-253-8

InChIKey

OTKXCALUHMPIGM-FQEVSTJZSA-N

SMILES

C(O)(=O)[C@H](CCC(OC(C)(C)C)=O)NC(OCC1C2=C(C=CC=C2)C2=C1C=CC=C2)=O

Appearance

Powder to crystal

Color

White to off-white

Storage

Store below +30℃.

pKa

3.70±0.10(Predicted)

Boiling Point

633.5±55.0 ℃(Predicted)

Density, g/cm3

1.232±0.06 (Predicted)

Melting Point

83-90 ℃

Refractive Index

-4 ° (C=1, 80% AcOH)

Optical Activity

[α]20/D 5.0±2.0°, c = 1% in acetic acid: water (4:1)

HOURS

Daily: 9.30 AM–6.00 PM
Sunday : 9.30 AM–1.00 PM
Holidays: Closed

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