Cat Number: API67732

Fluocinolone Acetonide

APIs
CAS Number
67-73-2
Description
Fluocinolone Acetonide is a synthetic glucocorticoid VEGF inhibitor.
MolecularWeight
452.49
MolecularFormula
C24H30F2O6
Appearance
Crystalline powder
Solubility
Soluble in water (partly), DMSO, alcohol ( ), chloroform, and methanol.
Storage
Store at room temperature
MeltingPoint
267-269℃ (lit.)
BoilingPoint
~578.5℃ at 760 mmHg
Density
~1.4 g/cm3
RefractiveIndex
1.58
OpticalActivity
α20D +100.1, c = 1.02 in chloroform; α20D +103±3, c = 1 in methanol; α25D +95 in chloroform
IC50
GR: IC50 = 3.13 nM (human); Progesterone receptor: IC50 = 26 nM (bovine)
pKValue
pKa: 12.78
FlashPoint
303.7±30.1 ℃
VapourPressure
0.0±3.6 mmHg at 25℃
PreparationUse
indicated for the relief of the inflammatory and pruritic manifestations of corticosteroid-responsive dermatoses.
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