Description
Fluocinolone Acetonide is a synthetic glucocorticoid VEGF inhibitor.
MolecularFormula
C24H30F2O6
Appearance
Crystalline powder
Solubility
Soluble in water (partly), DMSO, alcohol ( ), chloroform, and methanol.
Storage
Store at room temperature
MeltingPoint
267-269℃ (lit.)
BoilingPoint
~578.5℃ at 760 mmHg
OpticalActivity
α20D +100.1, c = 1.02 in chloroform; α20D +103±3, c = 1 in methanol; α25D +95 in chloroform
IC50
GR: IC50 = 3.13 nM (human); Progesterone receptor: IC50 = 26 nM (bovine)
VapourPressure
0.0±3.6 mmHg at 25℃
PreparationUse
indicated for the relief of the inflammatory and pruritic manifestations of corticosteroid-responsive dermatoses.