Cat Number: API50271

Estriol

Inquiry

CAS Number

50-27-1

Description

Estriol is an estradiol metabolite shown to protect against mammary carcinogenisis.

MolecularWeight

288.38

MolecularFormula

C18H24O3

Solubility

Soluble in pyridine (50 mg/ml), ethanol (10 mg/ml at 25℃), DMSO (57 mg/ml at 25℃), DMF (~30 mg/ml), and water (0.5 mg/ml at 25℃).

Storage

Store at -20℃

MeltingPoint

280-282℃ (lit.)

BoilingPoint

~469.0℃ at 760 mmHg

Density

~1.3 g/cm³

RefractiveIndex

1.62

OpticalActivity

α25D +58±4, c = 0.4 in dioxane; α20D +63.7, c = 1 in ethanol

IC50

ERα: IC50 = 1.69 nM (human); Arachidonate 15-lipoxygenase: IC50 = 8.64 µM (Oryctolagus cuniculus); ST: IC50 = 10.34 µM (human); GR: IC50 = 39.35 µM (human); Androgen Receptor: IC50 = 436.52 µM (rat)

pKValue

pKa: 10.25

PreparationUse

a weak estrogen used to treat vaginal dryness and estrogen deficiency conditions, such as vaginitis and vulvar itching.

HOURS

Daily: 9.30 AM–6.00 PM
Sunday : 9.30 AM–1.00 PM
Holidays: Closed

INFORMATION

Tel:
E-mail:
Address:
WhatsAPP

Member of