Cat Number: PIPE-0767

β-Estradiol

APIs
CAS Number
50-28-2
Synonyms
estradiol
beta-Estradiol
17beta-Estradiol
Oestradiol
Description
Estradiol is a naturally occurring hormone circulating endogenously in females. It is commercially available in several hormone therapy products for managing conditions associated with reduced estrogen, such as vulvovaginal atrophy and hot flashes. Some available forms of estradiol include oral tablets, injections, vaginal rings, transdermal patches, sprays, gels, and creams. When used for oral or IM administration, estradiol is commonly synthesized as a pro-drug ester (such as [DB13952], [DB13953], [DB13954], [DB13955], and [DB13956]). Because it has a low oral bioavailability on its own, estradiol is commonly formulated with an ester side-chain. [DB00977] (EE) is a synthetic form of estradiol commonly used as the estrogenic component of most combination oral contraceptive pills (OCPs). Ethinyl estradiol is different from estradiol due to its higher biovailability and increased resistance to metabolism, rendering it more suitable for oral administration.
Molecular Weight
272.4
Molecular Formula
C18H24O2
EINECS
200-023-8
SMILES
CC12CCC3C(C1CCC2O)CCC4=C3C=CC(=C4)O
Appearance
White powder.
Storage
Room temperature
Purity
HPLC≥98%
Boiling Point
445.9±45.0
Density, g/cm3
1.2±0.1
Melting Point
178-179 ℃
Refractive Index
1.599
Expiration Time
2years
Applications
human sex hormone
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