Cat Number: API50282

Estradiol

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CAS Number

50-28-2

Description

β-Estradiol is an ER agonist and activator of PI 3-kinase.

MolecularWeight

272.38

MolecularFormula

C18H24O2

Solubility

Soluble in DMSO (100 mM), ethanol (75 mM), Dimethylsulfoxide, water

Storage

Store at room temperature

MeltingPoint

176-180℃ (lit.)

BoilingPoint

~445.9℃ at 760 mmHg

Density

~1.2 g/cm³

RefractiveIndex

1.6

OpticalActivity

α20D +76.8, c = 1 in Dioxane

IC50

Estrogen receptor: IC50 = 0.01 nM (human); SK-BR-3: IC50 = 0.1 nM (human); MCF7: IC50 = 0.32 nM (human); ERα : IC50 = 0.57 nM (human)

pKValue

pKa: 10.27

FlashPoint

209.6±23.3 ℃

VapourPressure

0.0±1.1 mmHg at 25℃

PreparationUse

an estrogenic steroid used to treat vasomotor symptoms of vulvar and vaginal atrophy in menopause, hypoestrogenism, prevention of postmenopausal osteoporosis, treatment of breast cancer, and advanced androgen-dependent carcinoma of the prostate.

HOURS

Daily: 9.30 AM–6.00 PM
Sunday : 9.30 AM–1.00 PM
Holidays: Closed

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