Cat Number: API970741

epigallocatechin

CAS Number

970-74-1

Description

(-)-Epigallocatechin is the most abundant flavonoid in green tea, can bind to unfolded native polypeptides and prevent conversion to amyloid fibrils.

MolecularWeight

306.267

MolecularFormula

C15H14O7

SMILEs

C1[C@H]([C@H](OC2=CC(=CC(=C21)O)O)C3=CC(=C(C(=C3)O)O)O)O

Appearance

white powder

Solubility

Soluble in water, DMSO, methanol, and acetone.

Storage

Store at 4℃

MeltingPoint

208-210℃

BoilingPoint

685.6±55.0 ℃ at 760 mmHg

Density

1.7±0.1 g/cm³

RefractiveIndex

1.776

OpticalActivity

α20D -50, c = 0.04 in ethanol; α20D -56.2, c = 1 in acetone : water = 1 : 1

IC50

Superoxide-scavenging activity: IC50 = 480 nM; H9: IC50 = 5.88 µM (human); Enoyl-acyl-carrier protein reductase: IC50 = 7 µM (Plasmodium falciparum); DPPH radical scavenging activity: IC50 = 16.2 µM; Human recombinant ribonuclease H: IC50 = 16.4 µM

pKValue

pKa: 9.02

FlashPoint

368.5±31.5 ℃

VapourPressure

0.0±2.2 mmHg at 25℃

PreparationUse

Antioxidant activity. A potent inhibitor of amyloidogenic cystatin I66Q amyloid fibril formation in vitro.

HOURS

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Sunday : 9.30 AM–1.00 PM
Holidays: Closed

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