Description
Emedastine difumarate is an orally active, selective and high affinity histamine H1 receptor antagonist with a Ki value of 1.3 nM. Emedastine difumarate is a benzimidazole derivative with potent antiallergic properties and used for allergic rhinitis, allergic skin diseases and allergic conjunctivitis.
MolecularFormula
C25H34N4O9
Solubility
Soluble in water, sparingly soluble in anhydrous ethanol, very slightly soluble in acetone.
BoilingPoint
446.6ºC at 760 mmHg
PreparationUse
a histamine H1 receptor antagonist. used in the treatment of allergic conjunctivitis.
QualitySpecification
USP/EP