Cat Number: API136434349

Duloxetine Hydrochloride

CAS Number

136434-34-9

Description

Duloxetine Hydrochloride is a dual serotonin and norepinephrine reuptake inhibitor.

MolecularWeight

333.88

MolecularFormula

C18H19NOS•HCl

SMILEs

CNCC[C@@H](C1=CC=CS1)OC2=CC=CC3=CC=CC=C32.Cl

Appearance

Crystalline

Solubility

Soluble in water (5 mg/ml), methanol, DMSO (67 mg/ml at 25℃), and ethanol

Storage

Store at -20℃

MeltingPoint

162-166℃

BoilingPoint

466.2ºC at 760 mmHg

RefractiveIndex

~1.63

OpticalActivity

α20D 120.5±4.5, c = 1 in methanol; α20D +123.54, c = 0.84 in methanol

IC50

5-HT reuptake: IC50 = 28 nM (rat hippocampal slices); NA reuptake: IC50 = 46 nM (rat hippocampal slices)

pKValue

pKa: 9.5 (secondary amine)

FlashPoint

235.7ºC

PreparationUse

he salt form of antidepressant drug duloxetine, used for the treatment of depression and the treatment of stress urinary incontinence

HOURS

Daily: 9.30 AM–6.00 PM
Sunday : 9.30 AM–1.00 PM
Holidays: Closed

INFORMATION

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