Cat Number: API77883433

Doxazosin Mesylate

APIs
CAS Number
77883-43-3
Synonyms
Doxazosin mesylate
Cardura
Carduran
Cardular
Description
Doxazosin mesylate selectively antagonizes alpha-1-adrenergic receptors in smooth muscle of the bladder neck and prostate, thereby relaxing the smooth muscle and decreasing the obstruction and urethral resistance seen with benign prostate hyperplasia (BPH). This may improve BPH symptoms. This agent also blocks alpha-1-adrenergic receptors in peripheral vascular smooth muscle, which leads to vasodilatation and a subsequent decrease in peripheral vascular resistance.
Molecular Weight
547.6
Molecular Formula
C24H29N5O8S
EINECS
616-536-9
SMILES
COC1=C(C=C2C(=C1)C(=NC(=N2)N3CCN(CC3)C(=O)C4COC5=CC=CC=C5O4)N)OC.CS(=O)(=O)O
Therapeutic Area
Hypertension&Prostate Hyperphasia
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