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Cat Number: API77883433

Doxazosin Mesylate

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CAS Number

77883-43-3

Synonyms

Doxazosin mesylate
Cardura
Carduran
Cardular

Description

Doxazosin mesylate selectively antagonizes alpha-1-adrenergic receptors in smooth muscle of the bladder neck and prostate, thereby relaxing the smooth muscle and decreasing the obstruction and urethral resistance seen with benign prostate hyperplasia (BPH). This may improve BPH symptoms. This agent also blocks alpha-1-adrenergic receptors in peripheral vascular smooth muscle, which leads to vasodilatation and a subsequent decrease in peripheral vascular resistance.

Molecular Weight

547.6

Molecular Formula

C24H29N5O8S

EINECS

616-536-9

SMILES

COC1=C(C=C2C(=C1)C(=NC(=N2)N3CCN(CC3)C(=O)C4COC5=CC=CC=C5O4)N)OC.CS(=O)(=O)O

Therapeutic Area

Hypertension&Prostate Hyperphasia

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