Cat Number: INT4803741

Donepezil HCL Intermediates 1

CAS Number

4803-74-1

Synonyms

5,6-Dimethoxy-2-(pyridine-4-yl)methylene-indan-1-one
5,6-Dimethoxy-2-(pyridin-4-ylmethylene)-2,3-dihydro-1H-inden-1-one
(2E)-5,6-DIMETHOXY-2-(PYRIDIN-4-YLMETHYLIDENE)-3H-INDEN-1-ONE

Description

5,6-Dimethoxy-2-(4-pyridylmethylene)-1-indanone is one of Donepezil impurities. Donepezil, a highly specific reversible acetylcholinesterase (AChE) inhibitor, is used to treat moderate to severe Alzheimer's disease.

Molecular Weight

281.31

Molecular Formula

C17H15NO3

SMILES

COC1=C(C=C2C(=C1)CC(=CC3=CC=NC=C3)C2=O)OC

Appearance

Yellow solid

Boiling Point

499.9±45.0 ℃ (Predicted)

Density, g/cm3

1.255 (Predicted)