Cat Number: PIPB-0206

DMT-dT Phosphoramidite

CAS Number

98796-51-1

Synonyms

5'-O-DMT-thymidine 3'-CE phosphoramidite;DMT-dT PhosphoraMidite;5'-O-[Bis(4-Methoxyphenyl)phenylMethyl]-thyMidine 3'-[2-cyanoethyl N,N-bis(1-Methylethyl)phosphoraMidite];5′-O-(4,4′-dimethoxytrityl)-2′-deoxythymidine-3′-O-[O-(2-cyanoethyl)-N,N′-diisopropylphosphoramidite];5'-O-DMT-2'-deoxythymidine-3'-CE Phosphoramidite;5'-O-(4,4'-Dimethoxytrityl)-2'-deoxy-5-methyluridine-3'-O-[(2-cyanoethyl)-(N,N-diisopropyl)]phosphoramidite;5'-O-(4,4'-Dimethoxytrityl)-thymidine-3'-cyanoethyl Phosphoramidite;5'-O-(4,4'-DIMETHOXYTRITYL)-2'-DEOXYTHYMIDINE-3'-(2-CYANOETHYL-N,N-DIISOPROPYL)PHOSPHORAMIDITE

Description

DMT-dT Phosphoramidite is a nucleotide and reactant used in the solid-phase synthesis of phosphorothioate oligonucleotides, and in the synthesis of lipophilic 5-phosphoramidate derivatives of DNA and RNA oligonucleotides.

Molecular Weight

744.81

Molecular Formula

C40H49N4O8P

EINECS

685-410-3

InChI

UNOTXUFIWPRZJX-DJKSPSSYNA-N

InChIKey

UNOTXUFIWPRZJX-DJKSPSSYNA-N

SMILES

O(C(C1=CC=C(OC)C=C1)(C1=CC=C(OC)C=C1)C1=CC=CC=C1)C[C@H]1O[C@@H](N2C=C(C)C(=O)NC2=O)C[C@@H]1OP(N(C(C)C)C(C)C)OCCC#N |&1:25,27,38,r|

Appearance

powder or granules

Color

white to off-white

Storage

Sealed in dry,2-8℃

Purity

≥99%

pKa

9.55±0.10(Predicted)

Density, g/cm3

1.22 at 20℃

Vapour Pressure

0-0Pa at 20-50℃

Specification

100 g;kg

HOURS

Daily: 9.30 AM–6.00 PM
Sunday : 9.30 AM–1.00 PM
Holidays: Closed

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