Cat Number: PIPB-0208

DMT-dG(ib) Phosphoramidite

CAS Number

93183-15-4

Synonyms

dG(N-ibu)Phosphoramidite;N-blocked-5'-O-DMT 3'-CED deoxyguanosine phosphoramidite;5'-O-(4,4-Dimethoxytrityl)-N-isobutyryl-2'-deoxyguanosine-3'-(2-cyanoethyl-N,N-diisopropyl)phosphoramidite;5'-O-(4,4'-DIMETHOXYTRITYL)-N2-ISOBUTYRYL-2'-DEOXYGUANOSINE-3'-(2-CYANOETHYL-N,N-DIISOPROPYL)PHOSPHORAMIDITE;N2-(ISOBUTYRYL)-5'-O-(DIMETHOXYTRITYL)-2'-DEOXYGUANOSINE-3'-N,N-DIISOPROPYL (CYANOETHYL) PHOSPHORAMIDITE

Description

DMT-dG(ib) Phosphoramidite is used to prepare antisense oligonucleotides containing conformationally constrained methoxyaminomethylene and aminooxymethylene and aminomethylene bridged nucleoside analogs.

Molecular Weight

839.92

Molecular Formula

C44H54N7O8P

EINECS

685-519-6

InChI

FDRMKYVTIFSDPR-MMROLVBFSA-N

InChIKey

FDRMKYVTIFSDPR-MMROLVBFSA-N

SMILES

C(OC[C@H]1O[C@@H](N2C=NC3C(=O)NC(NC(=O)C(C)C)=NC2=3)C[C@@H]1OP(OCCC#N)N(C(C)C)C(C)C)(C1=CC=CC=C1)(C1=CC=C(OC)C=C1)C1=CC=C(OC)C=C1 |&1:3,5,23,r|

Appearance

powder or granules

Color

white to off-white

Storage

Sealed in dry,2-8℃

Purity

≥99%

pKa

9.16±0.20(Predicted)

Density, g/cm3

1.22 at 20℃

Vapour Pressure

0-0Pa at 20-50℃

Specification

100 g;kg

HOURS

Daily: 9.30 AM–6.00 PM
Sunday : 9.30 AM–1.00 PM
Holidays: Closed

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