Cat Number: PIPB-0208

DMT-dG(ib) Phosphoramidite

APIs
CAS Number
93183-15-4
Synonyms
dG(N-ibu)Phosphoramidite;N-blocked-5'-O-DMT 3'-CED deoxyguanosine phosphoramidite;5'-O-(4,4-Dimethoxytrityl)-N-isobutyryl-2'-deoxyguanosine-3'-(2-cyanoethyl-N,N-diisopropyl)phosphoramidite;5'-O-(4,4'-DIMETHOXYTRITYL)-N2-ISOBUTYRYL-2'-DEOXYGUANOSINE-3'-(2-CYANOETHYL-N,N-DIISOPROPYL)PHOSPHORAMIDITE;N2-(ISOBUTYRYL)-5'-O-(DIMETHOXYTRITYL)-2'-DEOXYGUANOSINE-3'-N,N-DIISOPROPYL (CYANOETHYL) PHOSPHORAMIDITE
Description
DMT-dG(ib) Phosphoramidite is used to prepare antisense oligonucleotides containing conformationally constrained methoxyaminomethylene and aminooxymethylene and aminomethylene bridged nucleoside analogs.
Molecular Weight
839.92
Molecular Formula
C44H54N7O8P
EINECS
685-519-6
InChI
FDRMKYVTIFSDPR-MMROLVBFSA-N
InChIKey
FDRMKYVTIFSDPR-MMROLVBFSA-N
SMILES
C(OC[C@H]1O[C@@H](N2C=NC3C(=O)NC(NC(=O)C(C)C)=NC2=3)C[C@@H]1OP(OCCC#N)N(C(C)C)C(C)C)(C1=CC=CC=C1)(C1=CC=C(OC)C=C1)C1=CC=C(OC)C=C1 |&1:3,5,23,r|
Appearance
powder or granules
Color
white to off-white
Storage
Sealed in dry,2-8℃
Purity
≥99%
pKa
9.16±0.20(Predicted)
Density, g/cm3
1.22 at 20℃
Vapour Pressure
0-0Pa at 20-50℃
Specification
100 g;kg
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