Cat Number: PIPB-0282

DMT-dC(Bz)-CE Phosphoramidite

CAS Number

102212-98-6

Synonyms

(2R,3S,5R)-5-(4-Benzamido-2-oxopyrimidin-1(2H)-yl)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)tetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite
N4-Benzoyl-2'-deoxy-5'-O-DMT-cytidine 3'-CE phosphoramidite
5'-O-(4,4'-Dimethoxytrityl)-N4-benzoyl-2'-deoxycytidine-3'-(2-cyanoethyl-N,N-diisopropyl)phosphoramidite

Description

5'-O-DMT-N4-Benzoyl-2'-deoxycytidine 3'-CE phosphoramidite is a highly versatile and efficient synthetic reagent for chemical researchers seeking to incorporate a benzoyl group at the N4 position of 2'-deoxycytidine in modified DNA oligonucleotides. This compound has demonstrated significant potential in combating viral infections, genetic disorders, and cancer. Its widespread use in the chemical research community speaks to its power in catalyzing complex reactions and enabling the creation of intricately modified nucleic acid constructs.

Molecular Weight

833.9

Molecular Formula

C46H52N5O8P

EINECS

801-520-8

SMILES

CC(C)N(C(C)C)P(OCCC#N)OC1CC(OC1COC(C2=CC=CC=C2)(C3=CC=C(C=C3)OC)C4=CC=C(C=C4)OC)N5C=CC(=NC5=O)NC(=O)C6=CC=CC=C6

Appearance

White to pale yellow powder

Purity

≥99%