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Cat Number: PIPB-0207

DMT-dA(bz) Phosphoramidite

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APIs
CAS Number
98796-53-3
Synonyms
N6-Benzoyl-2'-deoxy-3'-O-DMT-adenosine 5'-CE phosphoramidite;N6-Benzoyl-2'-deoxy-5'-O-DMT-adenosine 3'-CE phosphoramidite;2'DEOXYADENOSINE PHOSPHORAMADITE;2'-DEOXYADENOSINE PHOSPHORAMIDITE;dA(N-Bz)Phosphoramidite;N-blocked-5'-O-DMT 3'-CED deoxyadenosine phosphoramidite;(2R,3S,5R)-5-(6-benzamido-9H-purin-9-yl)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)tetrahydrofuran-3-yl 2-cyanoethyl diisopropylphosphoramidite
Description
DMT-dA(bz) Phosphoramidite is used to prepare antisense oligonucleotides containing conformationally constrained methoxyaminomethylene and aminooxymethylene and aminomethylene bridged nucleoside analogs.
Molecular Weight
857.93
Molecular Formula
C47H52N7O7P
EINECS
685-521-7
InChI
GGDNKEQZFSTIMJ-AKWFTNRHSA-N
InChIKey
GGDNKEQZFSTIMJ-AKWFTNRHSA-N
SMILES
O(C(C1=CC=C(OC)C=C1)(C1=CC=C(OC)C=C1)C1=CC=CC=C1)C[C@H]1O[C@@H](N2C3C(=C(N=CN=3)NC(=O)C3=CC=CC=C3)N=C2)C[C@@H]1OP(N(C(C)C)C(C)C)OCCC#N
Appearance
powder or granules
Color
white to off-white
Storage
Sealed in dry,2-8℃
Purity
≥99%
pKa
7.87±0.43(Predicted)
Density, g/cm3
1.23 at 20℃
Vapour Pressure
0-0Pa at 20-50℃
Specification
100 g;kg
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