Cat Number: PIPB-0225

DMT-2′O-Methyl-rC(ac) Phosphoramidite

CAS Number

199593-09-4

Synonyms

2'-OMe-Ac-CPhosphoramidite;2’-O-Methyl-rC(N-Ac)Phosphoramidite;5'-O-DMT-2'-O-Me-rC(N-Ac)-3'-CEDPA;N-Acetyl-5'-O-(4,4-dimethoxytrityl)-2'-O-methylcytidine-3'-(2-cyanoethyl-N,N-diisopropyl)phosphoramidite;(2R,3R,4R,5R)-5-(4-Acetamido-2-oxopyrimidin-1(2H)-yl)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-methoxytetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite;5'-DMT-2'-OMe-rC(N-Ac) Phosphoramidite;N4-Acetyl-5'-O-DMT-2'-O-methylcytidine 3'-CE phosphoramidite

Description

DMT-2′O-Methyl-rC(ac) Phosphoramidite is a nucleotide used in the solid-phase synthesis of phosphorothioate oligonucleotides using sulfurization byproducts for in situ capping.

Molecular Weight

801.86

Molecular Formula

C42H52N5O9P

EINECS

2017-001-1

InChI

WNWUMIPFLOKTEZ-UAQIPLLRSA-N

InChIKey

WNWUMIPFLOKTEZ-UAQIPLLRSA-N

SMILES

O(C(C1=CC=C(OC)C=C1)(C1=CC=C(OC)C=C1)C1=CC=CC=C1)C[C@H]1O[C@@H](N2C=CC(NC(C)=O)=NC2=O)[C@H](OC)[C@@H]1OP(N(C(C)C)C(C)C)OCCC#N |&1:25,27,39,42,r|

Appearance

powder

Color

white to off-white

Storage

Sealed in dry,2-8℃

Purity

≥98%

pKa

10.18±0.20(Predicted)

Melting Point

102 - 104℃

Specification

100 g;kg

HOURS

Daily: 9.30 AM–6.00 PM
Sunday : 9.30 AM–1.00 PM
Holidays: Closed

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