Synonyms
1,2-Distearoyl-sn-glycero-3-phosphocholine
DSPC
Distearoyl phosphatidylcholine
(R)-2,3-Bis(stearoyloxy)propyl (2-(trimethylammonio)ethyl) phosphate
Description
DSPC (1,2-Distearoyl-sn-glycero-3-phosphocholine) is a phosphatidylcholine, which is a phospholipid. It is a natural component of cell membranes and can be used to prepare lipid nanoparticles for mRNA vaccines. It forms part of the delivery system of Moderna and Pfizer COVID-19 vaccines. DSPC is used to produce non-pyrogenic liposomes capable of caging molecules.
Molecular Formula
C44H88NO8P
SMILES
CCCCCCCCCCCCCCCCCC(=O)OCC(COP(=O)([O-])OCC[N+](C)(C)C)OC(=O)CCCCCCCCCCCCCCCCC
Appearance
White to off-white solid