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Cat Number: API7413345

Disodium Methotrexate

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APIs
CAS Number
7413-34-5
Synonyms
Methotrexate disodium salt
METHOTREXATE SODIUM
methotrexate disodium
Sodium methotrexate
Description
An antineoplastic antimetabolite with immunosuppressant properties. It is an inhibitor of TETRAHYDROFOLATE DEHYDROGENASE and prevents the formation of tetrahydrofolate, necessary for synthesis of thymidylate, an essential component of DNA.
Molecular Weight
498.4
Molecular Formula
C20H20N8Na2O5
SMILES
CN(CC1=CN=C2C(=N1)C(=NC(=N2)N)N)C3=CC=C(C=C3)C(=O)NC(CCC(=O)[O-])C(=O)[O-].[Na+].[Na+]
EINECS
231-022-0
Appearance
Yellow Solid
Boiling Point
823℃
Melting Point
>255℃ (dec.)
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