Description
Diosmetin is a flavonoid that impedes human CYP1A enzyme activity and has anti-mutagenic and anti-allergenic properties
MolecularFormula
C16H12O6
SMILEs
COC1=C(C=C(C=C1)C2=CC(=O)C3=C(C=C(C=C3O2)O)O)O
Solubility
Soluble in water
BoilingPoint
576.7±50.0 ℃ at 760 mmHg
IC50
CYP1B1: IC50 = 29 nM (human); ABCC1: IC50 = 140 nM (human); CYP1A2: IC50 = 2.44 µM (human); MRP1: IC50 = 3 µM (human); MRP2: IC50 >50 µM (human)
VapourPressure
0.0±1.7 mmHg at 25℃
Specification
90-98% HPLC
PreparationUse
Antioxidant, antimutagenic and anti-mutagenic effects, inhibition of human CYP1A enzyme activity