Cat Number: API512049

Diosgenin

CAS Number

512-04-9

Description

Diosgenin, a steroidal saponin present in various plant species. Diosgenin is employed to synthesize progesterone, a hormone crucial for addressing menopausal symptoms and contraception. While the complete mechanism of action for diosgenin remains elusive, research indicates its ability to influence key enzymes and receptors. For instance, studies have demonstrated its capacity to modulate the activity of cyclooxygenase-2 (COX-2), an enzyme involved in the production of pro-inflammatory compounds. Additionally, diosgenin has been observed to regulate the activity of nuclear factor-kappa B (NF-κB), a transcription factor responsible for governing inflammatory and immune responses.

MolecularWeight

414.62

MolecularFormula

C27H42O3

SMILEs

CC1C2C(CC3[C@@H]4CC=C5C[C@@H](O)CC[C@]5(C)C4CC[C@]23C)OC11CCC(C)CO1

Appearance

Crystalline

Solubility

Soluble in chloroform (50 mg/ml), ethanol (5 mg/ml at 25℃), water

Storage

Store at room temperature

MeltingPoint

206-212℃

BoilingPoint

527.1±50.0 ℃ at 760 mmHg

Density

1.1±0.1 g/cm³

RefractiveIndex

1.56

OpticalActivity

α20D 121.6, c = 1 in chloroform

FlashPoint

272.6±30.1 ℃

VapourPressure

0.0±3.1 mmHg at 25℃

Specification

Pharmaceutical Grade

PreparationUse

Antioxidant, antivascular calcification, antitumor, anti-inflammatory, anti-allergic, antiviral and anti-shock effects.

HOURS

Daily: 9.30 AM–6.00 PM
Sunday : 9.30 AM–1.00 PM
Holidays: Closed

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