Cat Number: PIPE-0613

Digoxin

APIs
CAS Number
20830-75-5
Synonyms
Lanoxin
12beta-Hydroxydigitoxin
Rougoxin
Description
A cardiac glycoside extracted from the foxglove plant, Digitalis lanata, it is used to control ventricular rate in atrial fibrillation and in the management of congestive heart failure with atrial fibrillation, but the margin between toxic and therapeutic doses is small. It has a role as an epitope, an anti-arrhythmia drug, a cardiotonic drug and an EC 3.6.3.9 (Na(+)/K(+)-transporting ATPase) inhibitor. It is a cardenolide glycoside and a steroid saponin. It is a conjugate acid of a digoxin(1-).
Molecular Weight
780.9
Molecular Formula
C41H64O14
EINECS
244-068-1
SMILES
CC1C(C(CC(O1)OC2C(OC(CC2O)OC3C(OC(CC3O)OC4CCC5(C(C4)CCC6C5CC(C7(C6(CCC7C8=CC(=O)OC8)O)C)O)C)C)C)O)O
Appearance
clear to white crystals or white crystalline powder
Storage
Room temperature
Purity
HPLC≥98%
pKa
13.5
Boiling Point
931.6
Density, g/cm3
1.36 at 20 ℃
Melting Point
230-265 ℃
Expiration Time
2years
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