Cat Number: CHE117924331

Di-tert-butyl N,N-diethylphosphoramidite

APIs
CAS Number
117924-33-1
Synonyms
DI-T-BUTYL N,N-DIETHYLPHOSPHORAMIDITE;DI-TERT-BUTYL DIETHYLPHOSPHORAMIDITE;DI-TERT-BUTYL N,N-DIETHYLPHOSPHORAMIDITE;DI-TERT-BUTYL-N,N-DIETHYLPHOSPHOROAMIDITE;DI-TERT-BUTYL DIETHYLPHOSPHORAMIDITE, TE CH., 93%;Diethyl diethylphosphoramidite;N,N-Diethyl-phosphoraMidous Acid Bis(1,1-diMethylethyl) Ester;Phosphoramidous acid, diethyl-, bis(1,1-dimethylethyl) ester
Description
A useful reagent for the efficient phosphorylative conversion of alcohols into their corresponding dibenzylphosphorotriesters. It is applied as a phosphitylating agent in water-soluble phosphate prodrugs of 1-propargyl-8-styrylxanthine derivatives, a2a-selective adenosine receptor antagonists.
Molecular Weight
249.33
Molecular Formula
C12H28NO2P
Appearance
Oil
Color
Clear Colourless
Storage
2-8°C
Purity
0.98
pKa
4.41±0.70(Predicted)
Boiling Point
39-41°C/0.3 mmHg (lit.)
Density, g/cm3
0.896 at 25°C (lit.)
Refractive Index
n20/D 1.434(lit.)
Flash Point
173 °F
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