Description
Deoxycorticosterone acetate is a steroid hormone produced by the adrenal gland that possesses mineralocorticoid activity and acts as a precursor to aldosterone.
MolecularFormula
C23H32O4
SMILEs
CC(=O)OCC(=O)[C@H]1CC[C@@H]2[C@@]1(CC[C@H]3[C@H]2CCC4=CC(=O)CC[C@]34C)C
Solubility
Soluble in methanol, ethanol (6 mg/mL at 25℃), chloroform (100 mg/mL), and DMSO (11 mg/mL at 25℃). Insoluble in water.
BoilingPoint
504.1±50.0 ℃ at 760 mmHg
OpticalActivity
α20D 182.8, c = 0.5 in chloroform; α20D +173.5±5.5, c = 1 in dioxane
VapourPressure
0.0±1.3 mmHg at 25℃
PreparationUse
endogenous neurosteroid, to induce hypertensive pregnancy. It has also been used to investigate the effect of low epicatechin dosing on the cardiovascular function of deoxycorticosterone acetate (DOCA)-salt hypertensive rats.