Cat Number: INT1034301080

Decitabine Intermediate CR

CAS Number

1034301-08-0

Synonyms

3',5'-Bis-O-(4-chlorobenzoyl)-2-deoxy-5-azacytosine
[(2R,3S,5R)-5-(4-amino-2-oxo-1,3,5-triazin-1-yl)-3-(4-chlorobenzoyl)oxyoxolan-2-yl]methyl 4-chlorobenzoate
1,3,5-Triazin-2(1H)-one,4-amino-1-[3,5-bis-O-(4-chlorobenzoyl)-2-deoxy-b-D-erythro-pentofuranosyl]-

Description

4-Amino-1-[3,5-bis-O-(4-chlorobenzoyl)-2-deoxy-β-D-erythro-pentofuranosyl]-1,3,5-triazin-2(1H)-one is a derivative of β-Decitabine which is used as cancer treatment, in particular to inhibit the growth of pancreatic endocrine tumor cell lines.

Molecular Weight

505.31

Molecular Formula

C22H18Cl2N4O6

SMILES

C1C(C(OC1N2C=NC(=NC2=O)N)COC(=O)C3=CC=C(C=C3)Cl)OC(=O)C4=CC=C(C=C4)Cl

EINECS

816-382-4

Appearance

White Solid

Melting Point

185-188ºC