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Cat Number: API863127779

Dasatinib Monohydrate

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APIs
CAS Number
863127-77-9
Synonyms
Dasatinib monohydrate
Dasatinib hydrate
Dasatinib (monohydrate)
BMS 35482503
Description
A pyrimidine and thiazole derived ANTINEOPLASTIC AGENT and PROTEIN KINASE INHIBITOR of BCR-ABL KINASE. It is used in the treatment of patients with CHRONIC MYELOID LEUKEMIA who are resistant or intolerant to IMATINIB.
Molecular Weight
506
Molecular Formula
C22H28ClN7O3S
SMILES
CC1=C(C(=CC=C1)Cl)NC(=O)C2=CN=C(S2)NC3=CC(=NC(=N3)C)N4CCN(CC4)CCO.O
Appearance
White or off-white powder
Melting Point
>223℃ (dec.)
Standard
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