Cat Number: API1110813314

Dacomitinib

CAS Number

1110813-31-4

Description

Dacomitinib is a specific and irreversible inhibitor of the ERBB family of kinases with IC50s of 6 nM, 45.7 nM and 73.7 nM for EGFR, ERBB2, and ERBB4, respectively.

Molecular Weight

469.939

Molecular Formula

C24H25ClFN5O2

Storage

Store at room temperature

Boiling Point

665.7±55.0 ℃ at 760 mmHg

Density, g/cm3

1.3±0.1

Flash Point

356.4±31.5 ℃

Vapour Pressure

0.0±2.0 mmHg at 25℃

Standard

Facility GMP

Specification

Irreversible small-molecule tyrosine kinase inhibitor (TKI) of tyrosine kinase human epidermal growth factor receptors (HER) 1 (EGFR), HER2, and HER4, a drug candidate for the treatment of non-small cell lung carcinoma.

Preparation Use

tablets

Qualification

DMF

HOURS

Daily: 9.30 AM–6.00 PM
Sunday : 9.30 AM–1.00 PM
Holidays: Closed

INFORMATION

Tel:
E-mail:
Address:
WhatsAPP

Member of