Cat Number: API458377

Curcumin

CAS Number

458-37-7

Description

Curcumin is a natural phenolic compound with diverse pharmacologic effects including anti-inflammatory, antioxidant, antiproliferative and antiangiogenic activities. Curcumin is an inhibitor of p300 histone acetylatransferase ((HATs)) and also shows inhibitory effects on NF-κB and MAPKs.

MolecularWeight

368.38

MolecularFormula

C21H20O6

Appearance

Powder

Solubility

Soluble in DMSO (25 mg/ml), acetic acid, 0.1M NaOH, 10mM Na2CO3, acetone, water (< 0.1 mg/ml), and chloroform. Insoluble in ethanol.

Storage

Store at room temperature

MeltingPoint

183 ℃

BoilingPoint

593.2±50.0 ℃ at 760 mmHg

Density

1.3±0.1 g/cm³

RefractiveIndex

1.42

IC50

5-lipoxygenase: IC50 = 8 µM; cyclooxygenase: IC50 = 52 µM; nitric oxide synthase in activated macrophages: IC50 = 6 µM

FlashPoint

209.7±23.6 ℃

VapourPressure

0.0±1.8 mmHg at 25℃

PreparationUse

Anti-inflammatory, antioxidant, antiproliferative and antiangiogenic and other activities

HOURS

Daily: 9.30 AM–6.00 PM
Sunday : 9.30 AM–1.00 PM
Holidays: Closed

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